Medication to Treat Borderline Personality Disorder


Borderline Personality Disorder (BPD) is a complex mental health condition characterized by unstable emotions, impulsivity, and difficulties with relationships. This particular condition was first described in 1938 by American psychoanalyst Adolph Stern and affects between one and six percent of the general population of the world. It even affects ten and twenty percent of people who are being treated for psychiatric disorders.

Fortunately, in addition to psychiatric treatment, there's medication that can help with symptoms of Borderline Personality Disorder. Medication can be used as part of a comprehensive treatment plan to manage symptoms associated with BPD. Although there is no specific medication approved by the FDA (or Food and Drug Administration if you want to use the full name) for BPD, certain medications help treat its symptoms.

One commonly prescribed class of medications for BPD is selective serotonin reuptake inhibitors (SSRIs). These medications, such as fluoxetine (Prozac) and sertraline (Zoloft), can help stabilize mood, reduce impulsivity, and alleviate symptoms of depression and anxiety commonly experienced by individuals with BPD.

Another class of medications that may be used is antipsychotics. These medications, including aripiprazole (Abilify) and olanzapine (Zyprexa), can help manage BPD symptoms such as mood swings, anger, and paranoid thoughts. They may also help reduce impulsivity and stabilize emotions. With these and more medications being developed for the future, it is possible that more people with BPD can be treated and made to live productive lives in the future.


1. Lieb, K., Zanarini, M. C., Schmahl, C., Linehan, M. M., & Bohus, M. (2004). Borderline personality disorder. The Lancet, 364(9432), 453-461.

2. Verheul, R., Herbrink, M., & Koeter, M. W. J. (2018). The efficacy of various modalities of psychotherapy for personality disorders: A systematic review of the evidence and clinical recommendations. International Review of Psychiatry, 30(3), 1-24.

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