It has been a mystery why some people live a perfectly normal life until experiencing a potentially deadly cardiac episode. Now, researchers present a possible explanation in a microscopic modification of a protein, which causes a mutation to turn harmful. The knowledge could help future diagnosis and drug regimens.
It is not uncommon for an athlete to have a heart attack while running. In fact, an immediate heart attack is considered the leading cause of death in athletes. But why people appear so healthy and immediately suffer from heart disease remains unknown. A new study by researchers at the University of Copenhagen has found that alcohol-induced death is one of the leading causes of heart attacks.
Dysfunction of proteins called cardiac sodium channels in the cell membranes of heart cells interferes with some of today's cardiovascular diseases. Proteins are generally responsible for controlling heart rate. However, it is not known why the protein suddenly stopped working properly after years of normal functioning.
In a new study, researchers in the university's department of drug design and pharmacology have found that sudden cardiac arrest can be caused by a combination of genetics and phosphorylation. Phosphorylation is a process that can modify a protein and change its function, and it still happens. These conditions can also be caused by stress or illness, scientists explain.
When genetic mutations and mutations are combined, the protein does not work, resulting in a heart attack. These changes also affect responses to drug use, they said.
The authors believe their findings provide a basis for further research on the role of phosphorylation in rapid cardiovascular disease and may help improve diagnostic and therapeutic applications.
Signs and symptoms requiring treatment
The heart will stop beating immediately due to a problem with the electrical system. Often a heart attack occurs without warning. A sudden heart attack can lead to dehydration, shortness of breath, and loss of consciousness. If not treated immediately, it can be fatal.
Sometimes a person may notice signs and symptoms before a heart attack. Signs of discomfort include shortness of breath, shortness of breath, weakness, tachycardia, palpitations, lightheadedness or lightheadedness, and fainting or near fainting. So if you notice any of these signs and symptoms, see your doctor or seek emergency medical help.
If you see someone who is unconscious and is not breathing normally, try CPR or just chest compressions. This will keep you alive until emergency services arrive. To perform CPR, apply force to the victim's chest at a rate of 100 to 120 beats per minute. Source.