Heart attack: Australian researchers are trying to develop a drug using the deadly spider venom

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According to the World Health Organization (WHO), heart disease is the number one cause of death in the world, killing an estimated 17.9 million people each year. Heart attacks and strokes are the cause of more than 4 in 5 cardiovascular deaths. In addition, one-third of these deaths occur in people under the age of 70. When a person has a heart attack, blood flow to the heart is reduced and oxygen to the heart muscle is deficient. As a result, the cellular environment becomes acidic, sending a message to the heart cells and dying.

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Reportedly, no drug was found to stop these signs of death. However, a team of researchers are working on potential treatments made from spider venom to help victims of heart attacks.

Spider venom to treat patients with a heart attack

Australian scientists, the habitat of the world's most dangerous creatures, say something new about spider venom that they believe could lead to a new class of drugs to help people suffering from heart attacks I found. This study tests the fennel web spider, which is considered one of the most dangerous spiders in the world. They have large and strong fangs that can pierce delicate nails and shoes.

Researchers at the University of Queensland and the Victor Chan Heart Institute in Sydney are developing potential drug candidates derived from spider venom that block the "death signal" of the heart and kill heart cells after a heart attack. increase.

This potential treatment can be life-changing for patients with a heart attack

According to experts, there are no drugs in clinical trials that can prevent the damage caused by a heart attack, which can be a life-changing discovery. According to a study published in the journal Circulation, a protein known as Hi1a was found in the venom of the Funnel Web Spider on Fraser Island and could one day be used to treat the donor's heart. According to researchers, the transplant could be successful.

Researchers believe that it can also improve the number and quality of donor hearts and give hope to those on the waiting list for transplantation. However, Australian heart research is still in its infancy. In this study, researchers test candidate drugs by hitting human heart cells under the stress of a heart attack to see if they increase survival, and will conduct human clinical trials within the next few years. I want to get started.

Treatments available for heart attack

More heart tissue deteriorates or dies every minute after a heart attack. Rapid recovery of blood flow helps prevent heart damage. Treatment of a person diagnosed with a heart attack can be complicated. Common treatments are available:

1. Angioplasty is the procedure of passing a special tube containing a contracted balloon through the coronary arteries.

2. Artificial heart valve surgery replaces an abnormal or diseased heart valve with a healthy one.

3. Atherosctomy is similar to angioplasty, but the tip of the catheter contains a rotating razor that cuts plaque from the artery.

4. Bypass surgery cleanses the occluded arteries of the heart and allows blood to flow freely into the heart muscle.

5. Cardiomyoplasty is a research activity that involves removing skeletal muscle from the patient's back and abdomen.

6. Remove the damaged heart and donate a healthy human heart.

7. Minimally invasive heart surgery (MIHS) is a less invasive surgery that replaces traditional bypass surgery.

8. A catheter with electrode tips is passed through a vein through the myocardium, and high-frequency ablation destroys carefully selected cardiomyocytes in a very narrow area.

9. A stent is a mesh tube used to keep an artery open during angioplasty. TMR (Transmyocardial Revascularization) is a procedure that uses a laser to pierce a series of holes in the heart's pump chamber from the outside. Source

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