49ers News & Rumors: Awful Loss To Cardinals, Colt McCoy & James Conner | Defense Crushed

49ers news and rumors are sizzling hot following the 49ers disastrous 31-17 loss to the Arizona Cardinals in NFL week 9. The 49ers schedule opened up a golden opportunity for the 49ers to beat the first-place Cardinals without Kyler Murray with the Los Angeles Rams coming to Levi’s Stadium next week, but instead Colt McCoy and James Conner highlights vs. 49ers ended up being the talking point as the Cardinals THRASHED the 49ers defense under defensive coordinator DeMeco Ryans. 49ers Report host Chase Senior breaks down the latest 49ers news and rumors and brings you a 49ers postgame show following San Francisco’s 31-17 loss. #nfl

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